Serene Alexander Selected Research

4- (((4- (1- carboxy- 1- methylethoxy)- 7- methylquinolin- 2- yl)carbonyl)amino)- 5- (4- (ethoxycarbonyl)piperazin- 1- yl)- 5- oxopentanoic acid

5/2007

A novel P2Y(12) adenosine diphosphate receptor antagonist that inhibits platelet aggregation and thrombus formation in rat and dog models.

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Serene Alexander Research Topics

Disease

1	Myocardial Infarction 01/2008
1	Ischemic Stroke 01/2008
1	Hemorrhage 05/2007
1	Thrombosis (Thrombus) 05/2007
1	Disseminated Intravascular Coagulation 09/2006

Drug/Important Bio-Agent (IBA)

2	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 01/2008 - 05/2007
1	Adenosine Diphosphate (ADP)IBA 05/2007
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2007
1	4- ((4- (1- (ethoxycarbonyl)- 1- methylethoxy)- 7- methyl- 2- quinolyl)carbamoyl)- 5- (4- (ethoxycarbonyl)piperazin- 1- yl)- 5- oxopentanoic acidIBA 05/2007
1	4- (((4- (1- carboxy- 1- methylethoxy)- 7- methylquinolin- 2- yl)carbonyl)amino)- 5- (4- (ethoxycarbonyl)piperazin- 1- yl)- 5- oxopentanoic acidIBA 05/2007
1	Clopidogrel (Plavix)FDA Link 05/2007
1	Purinergic P2Y Receptor AntagonistsIBA 05/2007
1	Dacarbazine (DIC)FDA LinkGeneric 09/2006
1	Thromboplastin (Tissue Factor)IBA 09/2006
1	Indicators and Reagents (Reagents)IBA 09/2006

Therapy/Procedure

1	Oral Administration 05/2007
1	Intravenous Injections 09/2006